Preimplantation Genetic Diagnosis at PGD Science, Inc.
We are the institute founded in 2004 that provides PGD services for many respected IVF clinics in the United States.
PGD is an adjunctive procedure to In Vitro Fertilization (IVF). Therefore, controlled ovarian stimulation, egg retrieval, fertilization and embryo development occur as usual with IVF (procedure and risks discussed on IVF consent). PGD starts with embryo biopsy which can be performed on day 3, day 4 or day 5 of development. It is used to prevent genetic diseases or to select the most suitable embryos for transfer to establish a pregnancy.
Usually embryos are biopsied by our experienced embryologists using micromanipulation techniques to remove one cell without impacting the further development of the embryo.
The removed cell can be tested by several methods including:
- Polymerase Chain Reaction (PCR) for possible gene disorders
- Fluorescence in Situ Hybridization (FISH)
- Chromosomal Microarray Analysis (CMA) *
Embryo biopsy, analysis of the biopsied cells and delivery of the completed study to your IVF doctors may take from several hours to 2 days, depending on the types of study. The results of these studies will determine which embryos are selected for transfer.